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The spectrum of our activities and services

The spectrum of our activities and services is as vast and diverse as the colors of the rainbow. At the core of our spectrum is our commitment to providing exceptional customer service. We believe in going above and beyond to ensure that every interaction with our team is memorable and exceeds expectations. From the moment you reach out to us, you will experience our dedication to delivering personalized attention and tailored solutions.

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Cytotoxicity

Cytotoxicity plays a crucial role in assessing the potential of a drug to selectively target and destroy cancer or specific cells while minimizing harm to healthy cells. It is widely used throughout the drug development cycles.

We provide a variety of cytotoxicity assays for

  • Screening, selection, and improvement of drug candidates, including combination therapies
  • Dose-response and safety assessment
  • Confirmation of mechanism of action
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Potency

Potency assays are the most critical component of the drug lot release process because they assess the strength and effectiveness of a drug product, ensuring that each batch consistently meets requirement for quality, safety, and therapeutic efficacy. Each drug's uniqueness makes developing a specific potency assay challenging

Potency assays for various drug modalities.
For example:

  • DCC for antibody drugs
  • Cytokine secretion and cytotoxicity for CAR-immune cells
  • Virus neutralizing for therapeutic anti-viral drugs
  • Biological function changes due to gene expression or editing for gene therapy
  • Immune responses for vaccines
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Immunogenicity

Immunogenicity involves the body's immune system reacting to biological drugs, potentially affecting their effectiveness and safety. Pre-existing immunity due to prior exposure to similar or related substances or antigens also would impact drug’s efficacy and safety.

We specialize in assays to measure immune responses

  • Pre-existing immunity
  • Total antibody and neutralizing assays
  • T-cell based immunogenicity
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Single cell functionality

Single cell functionality analysis assesses individual behavior and attributes of these cells, enabling a deeper comprehension of cell-based therapies. Post-drug administration, comprehending the body's cellular-level responses to the drug is essential for a complete understanding of its effectiveness.

We develop novel single cell functionality assays

  • Single cell cytokine secretion – ELISPOT and modified assays
  • Single cell functional selection with the potential to recover cells for expansion or genetic analysis

Novel and Exclusive Assays

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Patient Derived Cancer Organoid

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